{"id":2627,"date":"2026-04-02T08:35:22","date_gmt":"2026-04-02T08:35:22","guid":{"rendered":"https:\/\/vienapaskola.lt\/index.php\/2026\/04\/02\/paryziuje-isikurusi-generare-surinko-20-mln-euru-kad-gautu-naujus-molekulinius-duomenis-vaistu-kurimui-is-mikrobu-genomu\/"},"modified":"2026-04-02T08:35:22","modified_gmt":"2026-04-02T08:35:22","slug":"paryziuje-isikurusi-generare-surinko-20-mln-euru-kad-gautu-naujus-molekulinius-duomenis-vaistu-kurimui-is-mikrobu-genomu","status":"publish","type":"post","link":"https:\/\/vienapaskola.lt\/index.php\/2026\/04\/02\/paryziuje-isikurusi-generare-surinko-20-mln-euru-kad-gautu-naujus-molekulinius-duomenis-vaistu-kurimui-is-mikrobu-genomu\/","title":{"rendered":"Pary\u017eiuje \u012fsik\u016brusi \u201eGenerare\u201c surinko 20 mln. eur\u0173, kad gaut\u0173 naujus molekulinius duomenis vaist\u0173 k\u016brimui i\u0161 mikrob\u0173 genom\u0173"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div>\n<p><span style=\"font-weight: 400;\"><strong>Generare<\/strong>Pary\u017eiuje \u012fkurtas Biotech startuolis, generuojantis naujus, auk\u0161tos kokyb\u0117s molekulinius duomenis vaist\u0173 k\u016brimui, dekoduodamas mikrob\u0173 genomus, surinko 20 mln. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Raundui vadovavo Alvenas ir Daphni, dalyvaujant visiems esamiems investuotojams, \u012fskaitant Galion.exe, Teampact Ventures ir VIVES Partners. <\/span><\/p>\n<p><span style=\"font-weight: 400;\"><strong>Guillaume&#8217;as Vandeneschas<\/strong>Generalinis direktorius ir vienas i\u0161 \u012fk\u016br\u0117j\u0173, Generare, sak\u0117, <em>&#8222;Vaist\u0173 atradimas turi duomen\u0173 problem\u0105. Visa sritis treniruoja savo modelius pagal t\u0105 pa\u010di\u0105 perdirbt\u0105 chemij\u0105 ir tikisi skirting\u0173 rezultat\u0173. Kli\u016btis yra ne algoritmai, o tikrai nauj\u0173, auk\u0161tos kokyb\u0117s molekulini\u0173 duomen\u0173 nebuvimas, ir mes tai sprend\u017eiame kurdami did\u017eiausi\u0105 patentuot\u0105 paslapting\u0173 ma\u017e\u0173 molekuli\u0173 duomen\u0173 rinkin\u012f. \u0160ios vaist\u0173 savyb\u0117s per 3 mlrd. biblioteka gali prilygti, paskatins kit\u0105 narkotik\u0173 atradim\u0173 \u0161imtmet\u012f.<\/em><\/span><\/p>\n<p><span style=\"font-weight: 400;\">2023 m. \u012fkurta daktaro Vincento Libiso ir Guillaume&#8217;o Vandenescho, patentuota \u201eGenerare\u201c platforma teigia i\u0161\u0161ifruojanti tai, k\u0105 para\u0161\u0117 gyvenimas. Jis skaito mikrob\u0173 genomus, i\u0161rei\u0161kia j\u0173 tyli\u0105j\u0105 chemij\u0105 ir generuoja naujus, auk\u0161tos kokyb\u0117s molekulinius duomenis, kuri\u0173 tr\u016bko kuriant vaistus. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Generare teigia, kad jis kuria auk\u0161\u010diausios kokyb\u0117s nepanaudotos molekulin\u0117s chemijos duomen\u0173 rinkin\u012f: augan\u010di\u0105 nauj\u0173 jungini\u0173 bibliotek\u0105, kuriai b\u016bdinga strukt\u016bra, biologinis aktyvumas ir vaist\u0173 potencialas.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bendrov\u0117s teigimu, vaist\u0173 atradimai de\u0161imtme\u010dius veik\u0117 toje pa\u010dioje siauroje chemin\u0117je erdv\u0117je, ne d\u0117l pasirinkimo, o d\u0117l to, kad u\u017e jos rib\u0173 nebuvo duomen\u0173. <em>\u201eKoduotas mikrob\u0173 genomuose yra molekulin\u0117s chemijos rezervuaras, kur\u012f evoliucija sugai\u0161o tris milijardus met\u0173, i\u0161 kuri\u0173 ma\u017edaug 97 % lieka neskaityti. \u201eGenerare\u201c generuoja tr\u016bkstamus duomenis tokios kokyb\u0117s ir masto, kokios dar nebuvo mat\u0119s laukas, tod\u0117l jie tikrai gali b\u016bti naudojami kuriant vaistus. <\/em>buvo pamin\u0117ta prane\u0161ime spaudai.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Patentuota didelio na\u0161umo klonavimo ir sekos nustatymo technologija, patvirtinta ERC finansuojamais akademiniais tyrimais ir daugybe recenzuot\u0173 publikacij\u0173, i\u0161\u0161ifruoja \u0161i\u0105 paslapting\u0105 chemij\u0105 dideliu mastu. \u012emon\u0117 tiria de\u0161imtis t\u016bkstan\u010di\u0173 mikrob\u0173 genom\u0173, identifikuoja gen\u0173 sekas, kurios grei\u010diausiai gamins bioaktyvias molekules, jas i\u0161rei\u0161kia ir apib\u016bdina gaut\u0173 jungini\u0173 strukt\u016br\u0105, biologin\u012f aktyvum\u0105 ir vaist\u0173 potencial\u0105. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Jame teigiama, kad jos kompetencija slypi ma\u017eose molekul\u0117se, junginiuose, atsakinguose u\u017e daugel\u012f \u017einomiausi\u0173 pasaulyje vaist\u0173, ir kiekviena nauja atrasta ma\u017ea molekul\u0117 papildo did\u0117jant\u012f duomen\u0173 rinkin\u012f, kuris ple\u010diasi su kiekvienu ciklu.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Generare&#8217;as mano, kad d\u0117l \u0161io derinimo ciklo jo duomen\u0173 rinkinys yra toks vertingas partneriams ir tampa dar svarbesnis, nes dirbtinis intelektas kei\u010dia vaist\u0173 atradim\u0105. Nors dirbtinis intelektas gali paspartinti nauj\u0173 vaist\u0173 k\u016brim\u0105, jis negali sukurti visi\u0161kai naujos chemijos tyrimams. Be nauj\u0173 duomen\u0173 modeliai ir toliau duos pana\u0161ius rezultatus, nepaisant j\u0173 sud\u0117tingumo. Pristatant tikrai naujas strukt\u016bras, atrinktas per evoliucinius procesus ir susietas su biologine veikla, j\u0173 veikimas labai pager\u0117ja.<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><em>&#8222;Gamta buvo pirmasis novatori\u0161k\u0173 vaist\u0173 veikimo b\u016bd\u0173 \u0161altinis, ir mes tik subrai\u017eome jos potencial\u0105. Kuriame infrastrukt\u016br\u0105, kad tai pakeistume, tur\u0117dami did\u017eiausi\u0105 pasaulyje komercin\u0119 evoliucijos b\u016bdu gaut\u0173 molekuli\u0173 bibliotek\u0105, duomen\u0173 rinkin\u012f, kuris tobul\u0117ja su kiekvienu ciklu, ir platform\u0105, kuri gali suteikti \u012fmon\u0117ms tikrai nauj\u0173 vaist\u0173 atradimo prad\u017eios ta\u0161k\u0173.<\/em> pasak\u0117 <strong>Daktaras Vincentas Libis<\/strong>CSO ir \u201eGenerare\u201c \u012fk\u016br\u0117jas. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u0160is naujas finansavimas leis \u201eGenerare\u201c iki 2027 m. de\u0161imt kart\u0173 padidinti \u0161\u012f paj\u0117gum\u0105 iki daugiau nei 2 000 molekuli\u0173, siekiant ilgainiui vir\u0161yti 10 000. Tai taip pat pad\u0117s beveik padvigubinti \u201eGenerare\u201c 25 ekspert\u0173 komand\u0105, kuri\u0105 sudaro skai\u010diavimo biologai, chemikai, sintetin\u0117s biologijos specialistai, technikai ir in\u017einieriai i\u0161 Pranc\u016bzijos, JK, JAV, Vokietijos, Australijos ir kit\u0173 \u0161ali\u0173. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bendrov\u0117s patar\u0117jai yra daktaras Frankas Petersenas, buv\u0119s Novartis Gamtini\u0173 produkt\u0173 chemijos departamento vykdomasis direktorius, ir profesor\u0117 Nadine Ziemert, pirmaujanti mikrob\u0173 biosintetini\u0173 gen\u0173 grupi\u0173 ekspert\u0117 Europoje.<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><em>\u201eNors \u201etechbio\u201c spartina vaist\u0173 atradim\u0105, \u201eGenerare\u201c stumia j\u012f toliau, pramoniniu mastu atidarydama gamtos vaistin\u0119. Panaudodama genomik\u0105, sintetin\u0119 biologij\u0105 ir ma\u0161inin\u012f mokym\u0105si, bendrov\u0117 generuoja patentuotus duomen\u0173 rinkinius apie ne\u017einomus veikimo mechanizmus, atveria vaist\u0173 galimybes, kuri\u0173 kiti nemato, ir stato griov\u012f, kuris jau sulaukia didelio pramon\u0117s susidom\u0117jimo.<\/em> pasak\u0117 <strong>Marija Tahri<\/strong>Bio Investor i\u0161 Alven. <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Vos per trejus metus \u201eGenerare\u201c tvirtina, kad ji tapo pirmaujan\u010dia platforma, gaminan\u010dia daugiau evoliucija pagr\u012fst\u0173 molekulini\u0173 duomen\u0173 nei bet kuri kita. Bendrov\u0117 pa\u017eymi, kad 2025 m. visi \u017eaid\u0117jai kartu atrado vos kelias de\u0161imtis nauj\u0173 molekuli\u0173; Vien Generare nustat\u0117 daugiau nei 200. Dabar \u0161ias molekules tyrim\u0173 laboratorijos naudoja kurdamos naujus vaistus nuo gyvybei pavojing\u0173 lig\u0173. <\/span><\/p>\n<\/div>\n<p><script>\n        !function(f,b,e,v,n,t,s)\n        {if(f.fbq)return;n=f.fbq=function(){n.callMethod?\n            n.callMethod.apply(n,arguments):n.queue.push(arguments)};\n            if(!f._fbq)f._fbq=n;n.push=n;n.loaded=!0;n.version='2.0';\n            n.queue=();t=b.createElement(e);t.async=!0;\n            t.src=v;s=b.getElementsByTagName(e)(0);\n            s.parentNode.insertBefore(t,s)}(window, document,'script',\n            'https:\/\/connect.facebook.net\/en_US\/fbevents.js');\n        fbq('init', '154586475232058');\n        fbq('track', 'PageView');\n    <\/script><br \/>\n<br \/><br \/>\n<br \/><a href=\"https:\/\/www.eu-startups.com\/2026\/04\/paris-based-generare-raises-e20-million-to-generate-novel-molecular-data-for-drug-development-from-microbial-genomes\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>GenerarePary\u017eiuje \u012fkurtas Biotech startuolis, generuojantis naujus, auk\u0161tos kokyb\u0117s molekulinius duomenis vaist\u0173 k\u016brimui, dekoduodamas mikrob\u0173 genomus, surinko 20 mln. Raundui vadovavo Alvenas ir Daphni, dalyvaujant visiems esamiems investuotojams, \u012fskaitant Galion.exe, Teampact Ventures ir VIVES Partners. Guillaume&#8217;as VandeneschasGeneralinis direktorius ir vienas i\u0161 \u012fk\u016br\u0117j\u0173, Generare, sak\u0117, &#8222;Vaist\u0173 atradimas turi duomen\u0173 problem\u0105. Visa sritis treniruoja savo modelius pagal t\u0105 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2628,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[3],"tags":[338,155,5022,5021,5026,360,8,156,5024,5025,20,5023,922,775,17,1294],"class_list":["post-2627","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-finansai","tag-duomenis","tag-euru","tag-gautu","tag-generare","tag-genomu","tag-is","tag-isikurusi","tag-kad","tag-kurimui","tag-mikrobu","tag-mln","tag-molekulinius","tag-naujus","tag-paryziuje","tag-surinko","tag-vaistu"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"GenerarePary\u017eiuje \u012fkurtas Biotech startuolis, generuojantis naujus, auk\u0161tos kokyb\u0117s molekulinius duomenis vaist\u0173 k\u016brimui, dekoduodamas mikrob\u0173 genomus, surinko 20 mln. Raundui vadovavo Alvenas ir Daphni, dalyvaujant visiems esamiems investuotojams, \u012fskaitant Galion.exe, Teampact Ventures ir VIVES Partners. Guillaume&#039;as VandeneschasGeneralinis direktorius ir vienas i\u0161 \u012fk\u016br\u0117j\u0173, Generare, sak\u0117, &quot;Vaist\u0173 atradimas turi duomen\u0173 problem\u0105. 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